Possible Reason for Rimonabant's Side Effects Discovered

The weight-loss drug rimonabant has been associated with troubling psychiatric side effects, and now researchers think they have discovered why.

A receptor in the brain called TRPV1, which is central to learning and memory, may...

Weight-Loss Drug Fights Alcoholic Fatty Liver Disease

Mice given the weight-loss drug rimonabant became resistant to alcohol's fat-building effects in the liver, which suggests the medication may help fight alcoholic fatty liver in humans, says a U.S. study.

Alcoholism is the...

NICE asks for more data on rimonabant

NICE has ruled against the use of the anti-obesity drug rimonabant in a preliminary recommendation.

The institute has asked the manufacturer Sanofi Aventis for more data on cardiovascular risk outcomes in patients who have...

Sanofi-Aventis faces challenges on obesity drug

French drugmaker Sanofi-Aventis SA  (SNY: 38.13, +0.59, +1.6%) is facing renewed challenges on its obesity drug Acomplia following the release Friday of two negative studies and the recent launch of a lawsuit against the...

Weight-loss drug increases chance of depression

People taking the weight-loss drug rimonabant have an increased risk of mental health problems, according to a study of more than 4,000 patients in four clinical trials. Those taking the drug were 40% more likely to suffer...